Progressive development of cardiomyopathy following altered autonomic 3 activity in status epilepticus
نویسنده
چکیده
1 2 Progressive development of cardiomyopathy following altered autonomic 3 activity in status epilepticus 4 5 M I Read, D M McCann, R N Millen, J C Harrison, D S Kerr, and I A Sammut, 6 Department of Pharmacology, University of Otago School of Medical Sciences, Dunedin, 7 New Zealand. 8 9 Running title: Sympathetic activity in seizure-induced cardiomyopathy. 10 11 ‡ Corresponding author: 12 Associate Professor Ivan A Sammut 13 Department of Pharmacology 14 University of Otago School of Medical Sciences, PO Box 913 15 Dunedin, Otago 9054, New Zealand 16 Tel:+64 3 479 5298 17 Fax:+64 3 479 9140 18 Email:[email protected] 19 20 21 Articles in PresS. Am J Physiol Heart Circ Physiol (September 4, 2015). doi:10.1152/ajpheart.00256.2015
منابع مشابه
Progressive development of cardiomyopathy following altered autonomic activity in status epilepticus.
Seizures are associated with altered autonomic activity, which has been implicated in the development of cardiac dysfunction and structural damage. This study aimed to investigate the involvement of the autonomic nervous system in seizure-induced cardiomyopathy. Male Sprague-Dawley rats (320-350 g) were implanted with EEG/ECG electrodes to allow simultaneous telemetric recordings during seizure...
متن کاملP-42: Protective Effects of Melatonin on The Testis in Post-Status Epilepticus Rats Following Lithium-Pilocarpin Injection As A Model of Temporal Lobe Epilepsy (TLE)
Background: Reproductive dysfunction and endocrine disorders are common among men with complex partial seizures of temporal lobe origin. More than 90% of men with epilepsy have abnormal semen analysis, including decreased sperm count, abnormal morphology, and impaired motility. The aim of this study was the assay of chronic treatment with melatonin during the latent phase and chronic phase of e...
متن کاملCardiac electrographic and morphological changes following status epilepticus: Effect of clonidine
PURPOSE Status epilepticus has been increasingly associated with cardiac injury in both clinical and animal studies. Our group has previously shown that excitotoxic seizure induction results in the formation of ischaemic myocardial infarcts and loss of cardiac haemodynamic function. We hypothesised that attenuation of cardiac sympathetic/parasympathetic balance with a central presynaptic α₂ ago...
متن کاملصرع پایدار مقاوم در کودکان، عوامل خطر، درمان و سرانجام زودرس
Introduction: Refractory status epilepticus is a life-threatening disease in children wherein seizure movements don't response to first line anti convulsion drugs. This study reviewed risk factors, management and early outcome of children with refractory status epilepticus. Methods: Patients with refractory status epilepticus admitted in Tabriz children's hospital between 2003 and 2006 were re...
متن کاملThe Efficacy of Propofol and Midazolam in Treatment of Refractory Status Epilepticus in Children
Background: In this study, we compared the efficacy and safety of propofol and midazolam in treatment of children’s refractory status epilepticus. Methods: We recruited 32 patients with refractory status epilepticus. Of those, 16 were treated primarily with midazolam and 16 received propofol. Results: We achieved complete seizure control in 6 (38%) patients treated by midazolam, and in 10 (63%)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2015